Genetic factors and environmental factors - lifestyle, personal and family medical history - need to be considered for a complete picture of risk assessment. This is because each of these types of risk factors has advantages and limitations in informing risk. For example, family medical history can capture general risk information for genetic factors inherited from one’s parents, but can be incomplete, unknown, or recalled inaccurately. Indeed, family medical history can often be one-dimensional and is affected by family size. Furthermore, family medical history is a summation of both genetic and environment factors, making it sometimes difficult to tease those.
