Medical research with animals has helped to extend and improve the quality of life for millions of people. It has had an equally far-reaching effect on pets and farm animals. This is why I accepted the invitation to write this report. It is based on a small selection of case histories that highlight key animal research contributions to the scientific revolution which has transformed healthcare. As a medical journalist for more than 30 years, I know about the critical role of animal research, and as an individual I have good reason for being grateful. I almost certainly owe my life to animal research