using stereotactic techniques (see footnote) to study the monkey MPTP model of PD led to the identification of new targets within the brain for deep brain stimulation (DbS) – targets include a structure called the subthalamic nucleus (STN). Continuous stimulation is delivered by an electrode wire inserted into this target and driven by a battery stimulator implanted under the collarbone. for many patients it has transformed their lives – and, unlike earlier surgical techniques, it does not destroy brain tissue so it can be reversed if scientists develop better treatments in the future. Professor john Stein, a neurophysiologist at.
