I am very grateful to the special group of distinguished scientists who made up the Panel and Secretariat for this major review of the evidence on food, nutrition, physical activity and cancer. The vision of WCRF International in convening this Panel and confidence in letting a strong-willed group of scientists have their way is to be highly commended. In our view, the evidence reviewed here that led to our recommendations provides a wonderful opportunity to prevent cancer and improve global health. Individuals and populations have in their hands the means to lead fuller, healthier lives. Achieving that will take action, globally, nationally, and locally, by communities, families,.