The ultimate goal of cancer research is the development of effective anticancer therapy. During the last several decades, the discovery of oncogenes, tumor suppressors, growth factors, signal transduction pathways has dramatically escalated our understanding of cancer cell biology and mechanisms of cell Hundreds of cellular proteins and pathways have been logically considered as molecular targets in a mechanism-based approaches of anticancer drug Yet, the progress in cancer treatment has not paralleled these dramatic achievements in basic research. Certainly, a delay must exist between identification of molecular targets and their clinical applications. However in many other fields of medicine, effective drugs had been found prior to identification of their.
