The scope of the Translational Medicine Ontology (TMO) is defined by the use case terminology and respective data sources. Each term and corresponding data source was analyzed for its conceptual, representational and reasoning capability as required by the use case requirements. TMO terms were obtained from a lexical analysis of sample research questions from 14 types of users, all of whom were involved in aspects of research, clinical care and or business (Table 2). Terms were formalized as referring to classes, relations or individuals in the OWL ontology. Terms that appear in state- ments that hold in general (. “patients participate in consultations” and “active ingredient is a.
