Translational medicine requires the full extent of patient data to be accessible so that questions spanning multiple data sources, such as those discussed above, can be asked and answered. For example, a physician in clinical practice would like to easily ask for the criteria for the diagnosis of a disease and the recommendations for perso- nalized medicines. However, TMKB has the potential to be equally relevant to scien- tists developing new pharmaceutical products. While simple questions may be answered by queries on a single data set, other scientific questions may be addressed only when diverse data sets are fully integrated [38]. Importantly, answering more sophisticated questions may require.
