As Chen [16] correctly pointed out, there are “many conflicting. (MRI). findings in individuals within the ASD.(which result from).factors such as population age, MRI acquisition parameters, details of the image processing pipeline, feature extraction procedures, analy- tic methods used to detect group differences and sample sizes.(which have).contributed to these disparities.”. From the entirety of MRI related studies, one may con- clude that ASD is typically associated with widely dis- tributed alterations of brain anatomy involving both grey and white matter, and with alterations in functional connectivity, which appear primarily decreased, yet also with some regionally increased connectivity. Despite a number of serious attempts, there are as yet no univer- sally established MRI-based criteria that.