In addition, more and more Parties are increasing their controls on the trade in medicines, thus improving the regulation of legal trade and more effectively combating illegal trade. This manual has proven to be an excellent tool judging from the fact that many additional copies of it were requested from the Secretariat. At CoP12, the Secretariat entered into an agreement to produce a second edition before CoP13, and I am pleased that this difficult work has been completed by the two original authors with contributions from various other organizations and individuals. This time a hard copy could not be produced as a consequence of the lack of.