A very important aspect to working with publisher is to work with different page sizes even though you may only be printing on A4 paper. Consider a leaflet that is A5 in size you may design it on screen using A5 size and then when you print you can tell publisher it is printing on A4. If the settings are correct then you can print two leaflets on the A4 paper while only working with the original single item onscreen. Similarly if there are 10 business cards per A4 sheet you may design just the one on screen but print that.
