"Although data concerning the response of pediatric hemodialysis patients to vaccination with standard pediatric doses are lacking, protective levels of antibody occur in 75% -97% of those who receive higher dosages (20-µg) on either the 3- or the 4-dose schedule."5 "Limited data are available on the duration of immune memory after hepatitis B vaccina tion in . . . dialysis patients. No clinically important HBV infections have been documented among immunocompromised persons who maintain protective levels of anti-HBsHowever, among hemodialysis patients who respond to the vaccine, clinically significant HBV infection has been documented in persons who have not maintained anti-HBs concentrations.
