Even incremental contributions to realizing improved health outcomes will deliver substantial social and economic benefits. When the funding request of $100 million for Canadian child health genomics research is compared to the short and long term benefits, it clearly delivers significant returns on investment. However, it must not be forgotten that it is fundamentally the lives of children that are at issue. In the words of a distinguished contributor to the development of this position paper who works in the field of childhood cancer: “there is a unique agony, a wrongness to the death of a child.” The importance.