There is a great difference between the superficial reading of a film and the proper interpretation of a clinical scintigraphic image by an imaging specialist. Fully utilizing the clinical image, the imaging specialist evaluates both the anatomical and the physiological structure of the human body. First the specialist must appreciate the patient’s clinical from this clinical context, he then applies his understanding of the pathophysiological basis of disease and his knowledge of how such pathology may translate into various imaging patterns. This awareness of the impact of pathophysiology on imaging studies is critical to the proper practice of nuclear medicine