Air pollution in general, especially air pollution from road traffic in particular in Hochiminh City (HCMC) are at the alarming. Using models to simulate air quality is needed to · manage and predict the air pollution levels. Research results have prepared emission inventory of air pollutants from road traffic, industry and domestic sources in HCMC. Besides, TAPQM and FVM models were used to simulate the meteorological conditions and air quality in HCMC. Emission inventory results from road traffic show that emission from motorcycles account for a significant amount of total load of pollutant emissions from that source. Simulation results of.