Search strategies were developed with PubMed using Medical Subject Heading [MeSH] and title abstract [tiab] terms to identify relevant exposures (organic vs. conventional production methods) and outcomes (composition of nutrient and other substances). The exposure terms searched (including all MeSH, headings, subheadings and tiab terms) were “organic”, “health food”, “conventional” combined with “food”, “agricultural crop”, “livestock”, “agriculture”. These were combined with a list of outcome terms for nutrients and other substances (see Appendix 1), modified from the World Cancer Research Fund specification manual (14). .