It is our pleasure to present the Proceedings of the 16th International Congress on Parkinson’s Disease (PD) and Related Disorders (16th ICPD) which took place in Berlin from June 5–9, 2005. This congress was the most successful congress ever with more than 3500 participants in the roaring German capital, consisting of an innovative program and with emphasis on bringing basic and clinical scientists together. Special attention has was paid in inviting young scientists. Therefore, the major aspect of scientific sessions was to identify young and up coming individuals in the field, with novel approaches to PD and novel models as a whole. The congress gave us the opportunity to present Germany.