A risk factor is anything that changes a person's chance of getting a disease such as cancer. Different cancers have different risk factors. For example, unprotected exposure to strong sunlight is a risk factor for skin cancer and smoking is a risk factor for cancers of the lungs, mouth, larynx, esophagus, bladder, and several other organs. Scientists have found few risk factors that make a person more likely to develop adrenal gland tumors. Even if a patient does have one or more risk factors for adrenal gland tumors, it is impossible to know for sure how much that risk factor.