A woman's hormone balance plays a part in most endometrial cancers. Many of the risk factors for endometrial cancer affect estrogen levels. Before change of life, the ovaries are the main source of the 2 main types of female hormones -- estrogen and progesterone. The balance between these hormones changes during a woman's menstrual cycle each month. A shift in the balance of these 2 hormones toward more estrogen increases a woman's risk for getting endometrial cancer. After change of life, the ovaries stop making these hormones, but a small amount of estrogen is still made in fat tissue
