(The cost-effectiveness analysis was based on the baseline screening results of the Morelos HPV study. 20 ) Results showed that using clinician-HPV testing alone or in combination with Pap is more cost-effective for women aged 30 to 80 years than using the Pap test alone in Mexico. The analysis took into account the cost of false negatives and false positives, colposcopy and biopsy, and treatment for CIN2/3 or cancer, as well as the cost of the screening tests. The combination of the clinician-HPV test with Pap was slightly more cost-effective than the clinician-HPV test alone, and detected 98 percent of all CIN2/3.