Association studies from north India probing multiple loci across the spectrum of candidate cytokine genes are scanty. The present study, therefore, was aimed to bring in focus certain unexplored polymorphisms in the context of tuberculosis susceptibility in north Indian population. The role and importance of genetic background in tuberculosis has now become univocal with ethnicity playing a crucial role. Probing new loci relating to tuberculosis susceptibility could suggest novel approach in pharmacogenomics and therapy to combat this pathogen. Also it could provide an insight into predicting individual’s genetic proneness to tuberculosis and of being future diagnostic tool for preventive therapy against tuberculosis
