This prospective observational study was undertaken at the Chest Clinic in Talera Hospital located in the Pimpri Chinchwad area of Pune. This clinic serves as the District TB Centre (DTC) for the Pimpri Chinchwad Municipal Corporation (PCMC) area under the Revised National Tuberculosis Control Programme of India. The DTC at Talera Hospital has a good record of implementation of the RNTCP and is located in an area with a high prevalence of HIV infection. Between 11 to 31 per cent of the new TB patients attending the Talera Clinic had concurrent HIV infection, similar to that reported earlier from other.