We newly identified an association between the haplotype [A-G-(insertion)-T] and susceptibility to pulmonary TB (p = , false discovery rate q = ). TB patients with systemic symptoms had a lower -196 to -174 deletion/deletion genotype frequency than those without systemic symptoms ( vs. ; p = ). TB patients with the deletion/deletion genotype had higher blood NK cell counts than those carrying the insertion allele (526 vs. cells/μl, p = ). TB patients with pleuritis had a higher 1350 CC genotype frequency than those without pleuritis ( vs. ; p = ). TB patients with the 1350 CC genotype had higher blood NK cell.
