Tuberculosis (TB) remains a worldwide health threat. One-third of the world’s population is currently infected with Mycobacterium tuberculosis that results in active or latent infection. TB causes nearly million deaths annually (Doherty et al., 2009). Because of the increasing mobility of the population, the changing environment, and the biology of bacilli, the prevalence of TB is higher in China. Epidemiological studies indicate that only 5 to 10% of people infected with M. tuberculosis develop active TB (van Crevel et al., 2002); the immune system can prevent the development of active disease. The genetic factors of TB have been studied using many methods, including selection of candidate.