We all know only too well that our way of life, the food we eat, smoking, stress or environmental toxins infl uence our health. But we have just started to learn how these environmental factors cooperate with our hereditary genetic dispositions to determine health or the development of diseases. Moreover, we did not know until recently that all these factors may also infl uence the health of our children and grandchildren to whom we may transmit functional changes of our genes. Are we really responsible for the well - being of our unborn descendants? Does nutrition or stress in our early childhood and in our daily life determine functions.