It has long been noted anecdotally that affect, psychological state and neurologic state have influences on inflammatory skin diseases. Disorders such as psoriasis, atopic dermatitis, acne and rosacea, among many others, are reported to become exacerbated by stress. Furthermore, it is widely believed that stress alters cutaneous immunity. However, mechanisms responsible for these effects have remained incompletely understood. Scientific evidence for an influence of the nervous system on immune and inflammatory processes in the skin has been developed only relatively recently. This area of research has now become intensely active and fruitful. Although neurocutaneous immunology is a young field, it is now accepted that the nervous system plays a major role in regulating immune and.
