After a successful MEDINFO in 1992, the Swiss Society for Medical Informatics hosts again a major event in medical informatics – the 19 th Medical Informatics Europe Conference, under the generic name of MIE2005. The host city, Geneva, is well known for its commitment in international healthcare, being the residence of several international organisations, including WHO. Geneva is also synonym with other major medical informatics achievements: the DIOGENE hospital information system and Natural Language Processing, both strongly connected to Geneva and its University Hospital.