Patient safety has become an important theme of the research agenda in the course of the last decade, both throughout Europe and worldwide. Improving patient safety and the quality of healthcare poses many challenges, and information technology (IT) has always been seen as having the potential to support the measures necessary to address these. But the risk of adverse events is unfortunately rising alongside the increasing sophistication and maturity of the health IT systems incorporated into the hospital environment. One major source of such errors is related to medication, . adverse drug events (ADEs), which can incur considerable extra healthcare costs, as well as posing a risk to.