Bioremediation, the use of microorganisms, by virtue of their bioconcentrating and metabolic properties, to degrade, sequester, or remove environmental contaminants, has about a 45-year history. Such uses of microorganisms for this purpose now involve freshwater, marine, and terrestrial environments. Bioremediation is a multidisciplinary area of knowledge and expertise that involves basic and applied science. Microbiologists, chemists, toxicologists, environmental engineers, molecular biologists, and ecologists have made major contributions to this subject