Brain morphology is in constant change from the very beginning of the neurodevelopment in human beings. The characterization of the brain morphology and its biological implications on a specific subject is a complex task which requires efficient computational approaches. Radiology has traditionally assessed the main brain changes in different alterations from a macroscopic point of view, thus, not considering subtle changes as a results of neuronal plasticity. In conjunction with functional information, the structural neuroimaging methods have established as the key in the diagnosis of several central nervous system disorders, including tumours, neurodegenerative disorders and psychiatric diseases
