Alzheimer’s disease, a neurodegenerative disorder causing synaptic impair-ment and neuronal cell death, is strongly correlated with aggregation of the amyloid-bpeptide (Ab). Divalent metal ions such as Cu 2+ and Zn 2+ are known to significantly affect the rate of aggregation and morphology of Abassembliesin vitro and are also found at elevated levels within cerebral plaquesin vivo.