This volume grew out of two conferences held in 2007 to address the opportunities and challenges of transition to a bio-economy. The first, an international sympo- sium on “Fueling Change with Renewable Energy,” was held at the University of Illinois at Urbana-Champaign in April 2007, while the second, “Intersection of Energy and Agriculture: Implications of Biofuels and the Search for a Fuel of the Future,” was held at the University of California at Berkeley in October 2007. We gratefully acknowledge financial support provided by the Energy Biosciences Institute, University of California at Berkeley; Giannini Foundation of Agricultural Economics, University of California; the Environmental Council, University of Illinois at Urbana-Champaign;.