Working on operational performance improvement projects in chemical industry gave me the opportunity to experience first hand the challenges this industry is faced with due to changes of the competitive landscape and the shift of demand growth to the developing regions of the world. Ad- dressing these challenges requires not only an operational but also a strate- gic response. The production (network) strategy is at the heart of the prob- lem for many companies. Decision makers in industry are aware of the need to adapt their production networks but lack adequate methodological support to holistically re-design them. The core objectives of my endeavor.