Despite evidence to the contrary, chemical industry critics of epidemiologic studies linking pesticides to major diseases argue that they are of limited value because of their reliance on records and study participants’ memory, among other issues. In fact, the correlation of patterns of chemical use with an effect is difficult to establish in epidemiology and therefore may underestimate hazard effects. When a correlation is established it raises serious concern. The epidemiologic studies in the Pesticide-Induced Diseases Database show an overall pattern that links pesticide exposure to major diseases. Inherent limitations, such as the following, only add to the power of.