Owing to theuseof porphyrins inphotodynamic therapy for the treatment of malignant tumors, and the preferential interaction of lectins with tumor cells, studies on lectin– porphyrin interactionareof significant interest. In this study, the interaction of several free-base and metalloporphyrins withMomordica charantia(bitter gourd) lectin (MCL) was investigated by absorption spectroscopy. Difference absorp-tion spectra revealed that significant changes occur in the Soret band region of the porphyrins on binding to MCL
