The double-stranded RNA-binding motif (dsRBM) is anabbbafold with a well-characterized function to bind structured RNA molecules. This motif is widely distributed in eukaryotic proteins, as well as in proteins from bac-teria and viruses. dsRBM-containing proteins are involved in processes ran-ging from RNA editing to protein phosphorylation in translational control and contain a variable number of dsRBM domains.