Tachykinins and tachykinin-related peptides (TKRPs) play major roles in signaling in the nervous system and intestine of both invertebrates and ver-tebrates. Here we have identified cDNAs encoding precursors of multiple TKRPs from the cockroachesLeucophaea maderaeandPeriplaneta ameri-cana. All nine LemTKRPs that had been chemically isolated in earlier experiments could be identified on the precursor ofL. maderae. Four previ-ously unidentified LemTKRPs were found in addition on the precursor.
