WhenSaccharomyces cerevisiaecells, grown in galactose, glucose or mannose, were treated with mMhydrogen peroxide (H2O2) for 30 min, an important decrease in the ATP, and a less extensive decrease in the GTP, CTP, UTP and ADP-ribose levels was estimated. Concomitantly a net increase in the inosine levels was observed. Treatment with 83mMmenadionepromoted theappearanceof acompound similar to adenosine but no appreciable changes in the nucleotide content of yeast cells, grown either in glucose or galactose