Flavoproteins are ubiquitous redox proteins that are involved in many biological the majority of flavoproteins, the flavin cofactor is tightlybut noncovalently dissociation of flavoproteins into apo-proteinandflavinprostheticgroupyields valuable insights in flavoprotein folding, of the natural cofactorwithartificial flavins has proved tobe especially useful for the determination of the solvent acces-sibility, polarity, reaction stereochemistry and dynamic behaviour of flavoprotein active sites
