The vanilloid-like TRP-channel VRL-1 (TRPV2) is a non-selective cation channel expressed by primary sensory neurons and non-neuronal tissues [Caterina, ., Rosen, ., Tominaga, M., Brake, and Julius, D. (1999) Nature398, 436–441]. It is one of the six members of the vanilloid-like TRP-channel family which is now termed the TRPV family [Montell, G., Birnbaumer, L., Flockerzi, V., Bindels, ., Brutford, ., Caterina, ., Clapham, ., Harteneck, C., Heller, S., Julius, D., Kojima, I., Mori, Y., Penner, R., Prawitt, D., Scharenberg, ., Schultz, G., Shimizu, N. and Zhu, . (2002)Mol. Cell 2, 229–231]. .
