A new NADP(H)-dependent alcohol dehydrogenase (the YCR105Wgene product, ADHVII) has been identified in Saccharomyces cerevisiae. The enzyme has been purified to homogeneity and found to be a homodimer of 40 kDa subunits and a pI of –. ADHVII shows a broad sub-strate specificity similar to the recently characterized ADHVI (64% identity), although they show some differ-ences in kinetic properties. ADHVI and ADHVII are the onlymembersof the cinnamyl alcohol dehydrogenase family inyeast. SimultaneousdeletionofADH6andADH7wasnot lethal for the yeast
