Due to this very detrimental environmental hazard experienced during this period by Zanzibar islands, with very sensitive and fragile ecosystem the Ministry of Health and Social Welfare in collaboration with WHO decided to develop these official and very comprehensive guidelines based on the National Drug Policy, WHO guidelines and the Zanzibar Food, Drugs and Cosmetics Act No 2/2006. Therefore these guidelines give appropriate measures of safe disposal to minimize the risks that could happen due to pharmaceutical waste. .