Hyperglycaemic complications were related to exposure to high glucose levels in plasma, and there were no major studies like the ROSSO and Kaiser studies for urine glucose monitoring. The evidence that plasma glucose monitoring could be replaced by urine glucose monitoring was found to be poor. Although the DiGEM study was published after the evidence cut-off date, it had been identified as potentially important on the basis of earlier information. However, at review the GDG felt that a study which viewed self-monitoring as a stand-alone intervention, and not as an element of a full educational programme, could not properly inform the appropriate use of selfmonitoring. The GDG further.
