The HN-06 compound was found as compatibilizer for natural rubber (NR)-chloroprene rubber (CR) blend. The blend containing wt% HN-06 compound gave good compatibility and it can be observed by scanning electron microscopy (SEM) image of two rubbers layer’s interface. Blend of NR/CR/HN-06 = 70/30/ wt% have high mechanical properties the tensile strength MPa, the tear strength N/mm, the abrasion loss g, good ozone and oil resistance.