Cis-[PtPy(o-toluidine)Cl2] (P1), cis-[PtPy(m-toluidine)Cl2] (P2), cis-[PtPy(p-toluidine)Cl2] (P3), cis-[PtPy(o-anizidine)Cl2] (P4), cis-[PtPy(m-anizidine)Cl2] (P5), cis-[PtPy(p-anizidine)Cl2] (P6) v( [Pt Py(m-toluidine)2Cl]Cl (P7) have been prepared. The structure of the complexes have been examined by elemental analysis, molar conductivity, UV, IR, Raman and NMR spectra. It is shown that P1÷ P6 have cis-configuration, two molecules m-toluidine of P7 bound to the Pt(II) in two cis- positions compared with the molecular pyridine. The complexes were tested for citotoxity and found that cis-[PtPy(o-toluidine)Cl2] (P1) exhibit anticancer (Hep-G2 and F1) activities at concentration 5 µg/ml.
