It is remarkable that the pathological state of human soft tissues highly correlates with static and low-frequency mechanical properties, particularly shear elasticity (., Sumi, 2005d). Accordingly, we have been developing ultrasonic (US)-strain measurement-based one- dimensional (1D) (Sumi et al., 1993, 1995a, 2010f; Sumi, 1999b, 2005d, 2008a, 2010d; Sumi & Matsuzawa, 2007b), 2D (Sumi et al., 1993, 1995a; Sumi, 1999c, 2005d, 2006b, 2007g, 2008a, 2008c, 2010d) and 3D (Sumi, 1999c, 2005d, 2006b, 2007g, 2010d.