Chapter 13 - Chromosomal rearrangements and changes in chromosome number. This chapter presents the following content: Rearrangements of DNA sequences, transposable genetic elements, rearrangements and evolution: a speculative comprehensive example, changes in chromosome number, emergent technologies: beyond the karyotype. | PowerPoint to accompany Genetics: From Genes to Genomes Fourth Edition Leland H. Hartwell, Leroy Hood, Michael L. Goldberg, Ann E. Reynolds, and Lee M. Silver Prepared by Mary A. Bedell University of Georgia Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition How Genes Travel on Chromosomes PART IV Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 13 Chromosomal Rearrangements and Changes in Chromosome Number Rearrangements of DNA Sequences Transposable Genetic Elements Rearrangements and Evolution: A Speculative Comprehensive Example Changes in Chromosome Number Emergent Technologies: Beyond the Karyotype CHAPTER OUTLINE CHAPTER Two main themes underlying the observations on chromosomal changes Karyotypes generally remain constant within a species Most genetic imbalances result in a selective disadvantage Related species usually have different karyotypes Closely-related species differ by only a few rearrangements Distantly-related species differ by many rearrangements Correlation between karyotypic rearrangements and speciation Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 13 Chromosomal rearrangements Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 13 Table Changes in chromosome number Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 13 Table (cont) Deletions: origin and detection Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 13 Fig. Symbols for a deletion are Del or Df (. Del/+ or Df/+ is a deletion heterozygote and Del/Del or Df/Df is a . | PowerPoint to accompany Genetics: From Genes to Genomes Fourth Edition Leland H. Hartwell, Leroy Hood, Michael L. Goldberg, Ann E. Reynolds, and Lee M. Silver Prepared by Mary A. Bedell University of Georgia Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition How Genes Travel on Chromosomes PART IV Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 13 Chromosomal Rearrangements and Changes in Chromosome Number Rearrangements of DNA Sequences Transposable Genetic Elements Rearrangements and Evolution: A Speculative Comprehensive Example Changes in Chromosome Number Emergent Technologies: Beyond the Karyotype CHAPTER OUTLINE CHAPTER Two main themes underlying the observations on chromosomal changes Karyotypes generally remain constant within a species Most genetic imbalances result in a selective disadvantage