Chapter 16 - Gene regulation in eukaryotes. The main contents of this chapter include all of the following: Overview of eukaryotic gene regulation, control of transcription initiation, chromatin structure and epigenetic effects, regulation after transcription, a comprehensive example: sex determination in Drosophila. | PowerPoint to accompany Genetics: From Genes to Genomes Fourth Edition Leland H. Hartwell, Leroy Hood, Michael L. Goldberg, Ann E. Reynolds, and Lee M. Silver Prepared by Mary A. Bedell University of Georgia Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition How Genes Are Regulated PART V Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 16 Gene Regulation in Eukaryotes Overview of Eukaryotic Gene Regulation Control of Transcription Initiation Chromatin Structure and Epigenetic Effects Regulation After Transcription A Comprehensive Example: Sex Determination in Drosophila CHAPTER OUTLINE CHAPTER Overview of eukaryotic gene regulation Eukaryotes use complex sets of interactions Regulated interactions of large networks of genes Each gene has multiple points of regulation Themes of gene regulation in eukaryotes: Environmental adaptation in unicellular eukaryotes Maintenance of homeostasis in multicellular eukaryotes Genes are turned on or off in the right place and time Differentiation and precise positioning of tissues and organs during embryonic development Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 16 Compared to prokaryotes, eukaryotes have additional levels of complexity for controlling gene expression Eukaryotic genomes are larger than prokaryotic genomes Chromatin structure in eukaryotes makes DNA unavailable to transcription machinery Additional RNA processing events occur in eukaryotes In eukaryotes, transcription takes place in the nucleus and translation takes place in the cytoplasm Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 16 Key regulatory differences between eukaryotes and prokaryotes Copyright © The | PowerPoint to accompany Genetics: From Genes to Genomes Fourth Edition Leland H. Hartwell, Leroy Hood, Michael L. Goldberg, Ann E. Reynolds, and Lee M. Silver Prepared by Mary A. Bedell University of Georgia Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition How Genes Are Regulated PART V Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Hartwell et al., 4th edition, Chapter 16 Gene Regulation in Eukaryotes Overview of Eukaryotic Gene Regulation Control of Transcription Initiation Chromatin Structure and Epigenetic Effects Regulation After Transcription A Comprehensive Example: Sex Determination in Drosophila CHAPTER OUTLINE CHAPTER Overview of eukaryotic gene regulation Eukaryotes use complex sets of interactions Regulated interactions of large networks of genes Each gene has multiple points of regulation Themes of gene regulation in .
