(BQ) Part 2 book "Dermatology acne" presentation of content: The Vasculopathic pattern, panniculitis, fibrosing dermatitis, the depositional pattern, the melanocytic tumors, epithelial neoplasms, adnexal neoplasms, the mesenchymal tumors. | World Clin Dermatol. 2013;1(1):128-43. Adult Acne *Alison M Layton MB ChB FRCP, Rebecca L Mawson MB ChB Bsc DRCOG Harrogate and District NHS Foundation Trust, Lancaster Park Road, Harrogate, HG2 7SX, London, UK ABSTRACT Acne remains as one of the commonest inflammatory dermatoses seen worldwide. While teenage acne is still regarded as a ‘rite of passage’ by many, it is increasingly acknowledged that acne is a chronic disease extending beyond teenage years and in some cases, presents for the first time well after adolescence. This article highlights key features of adult acne including debate around the definition, prevalence of the problem, underlying pathogenesis, and related epidemiological factors, as well as therapeutic options specific to management and related outcomes. Introduction Acne represents a polymorphic inflammatory skin problem centered on the pilosebaceous unit. It typically develops around adrenarche in association with an increase in androgen-mediated sebum production. Over the last decade, it has been recognized that acne is a chronic The peak age of onset for acne is 16–19 years in boys and 14–17 years in Seventy percent of cases resolve after 5 years of onset but in some cases, acne will either persist as a continuum until 20–30 years of age or present for the first time well after teenage DEFINING ADULT ACNE Defining a specific age for the onset of late-onset or adult acne is challenging, as it is dependent on individual maturity. A classification based on age of onset greater *Corresponding author Email: © 2014 Jaypee Brothers Medical Publishers. All rights reserved. World Clinic Dermatology (Acne).indd 128 30-11-2013 17:04:57 Adult Acne Figure 1: Moderate inflammatory acne in a male of 26 years. than 25 years, persistence beyond 21 years and/or relapse of acne post-adolescence has been suggested in the literature (Figure 1).3 Given adolescent acne is said to peak at the latest
