An enzyme-free glucose sensor has been developed based on electrodeposited gold nanoparticles modified screen-printed carbon electrode (SPCE). The combination of electrodeposited gold nanoparticles and SPCE, makes the device compact, low cost, and reliable enzyme-free glucose sensor. Gold nanoparticles were directly synthesized via electrochemical deposition method on carbon surface from HAuCl4 solution. | VNU Journal of Science: Natural Sciences and Technology, Vol. 32, No. 4 (2016) 83-89 Electrodeposited Gold Nanoparticles Modified Screen Printed Carbon Electrode for Enzyme-Free Glucose Sensor Application Nguyen Xuan Viet1,2,*, Yuzuru Takamura1 1 School of Materials Science, Japan Advanced Institute of Science and Technology (JAIST), 1-1 Asahidai, Nomi City, Ishikawa 923-1292, Japan 2 Faculty of Chemistry, VNU University of Science, 19 Le Thanh Tong, Hoan Kiem, Hanoi, Vietnam Received 06 July 2016 Revised 05 August 2016; Accepted 01 Septeber 2016 Abstract: An enzyme-free glucose sensor has been developed based on electrodeposited gold nanoparticles modified screen-printed carbon electrode (SPCE). The combination of electrodeposited gold nanoparticles and SPCE, makes the device compact, low cost, and reliable enzyme-free glucose sensor. Gold nanoparticles were directly synthesized via electrochemical deposition method on carbon surface from HAuCl4 solution. The gold nanoparticles electrodeposited on the surface of SPCE was observed by SEM. The gold nanoparticles modified SPCE were successfully used for the sensing of glucose. This enzyme free sensor showed wide linear range with the glucose concentration from ÷ mM and sensitivity µA/ with a limit of detection of 200 µM. Keywords: Enzyme Free Glucose Sensor, Screen-Printed Carbon Electrode, Electrodeposited Gold Nanoparticles. 1. Introduction* Accurate, rapid, inexpensive and stable sensor for glucose detection in biological fluids is nowadays extremely important for the diagnosis and management of diabetes mellitus. The majorities of well-known amperometric biosensors for glucose monitoring are based on immobilized specific oxidase and electrochemical detection of enzymatically liberated hydrogen peroxide, or redox mediators such as derivatives of ferrocene, hydroquinone and other redox organic dyes [1]. Although enzymatic glucose sensors usually shows good selectivity and sensitivity, the .
