Objectives: To evaluate the efficacy and safety of ultrasound-guided injection of platelet-rich plasma (PRP) in the treatment of supraspinatus tendonitis after 12 weeks of follow-up. Subjects and methods: A prospetive controlled clinical trial was followed up to 12 weeks in 44 patients with supraspinatus tendonitis. | Journal of military pharmaco-medicine n08-2017 INITIAL EVALUATION OF EFFICACY OF AUTOLOGOUS PLATELET-RICH PLASMA ULTRASOUND-GUIDED INJECTION IN SUPRASPINATUS TENDONITIS TREATMENT Nguyen Duc Phong*; Pham Hoai Thu*; Nguyen Van Hung* SUMMARY Objectives: To evaluate the efficacy and safety of ultrasound-guided injection of platelet-rich plasma (PRP) in the treatment of supraspinatus tendonitis after 12 weeks of follow-up. Subjects and methods: A prospetive controlled clinical trial was followed up to 12 weeks in 44 patients with supraspinatus tendonitis, who were divided into two groups: 22 patients (22 supraspinatus tendons) received a single ultrasound-guided injection of PRP into supraspinatus tendon sheath, 22 patients (22 supraspinatus tendons) were given a single ultrasound-guided injection of ml methylprednisolone acetate 40 mg/mL (Depo-Medrol) into supraspinatus tendon sheath. Results: After 12 weeks of treatment, there were improvement in VAS, abduction angle of shoulder joint and SPADI scores in the studied group: The average VAS and SPADI scores were decreased from to points and from to points, respectively. The average abduction angle of shoulder joint was increased from to , significantly higher than that in the control group (p ) and there was no serious complication in both groups. Conclusions: A single ultrasound-guided injection of PRP is more effective than a single ultrasound-guided injection of Depo-Medrol in treatment of supraspinatus tendonitis. The procedure is a safe theraputic intervention. * Keywords: Supraspinatus tendonitis; Autologous platelet-rich plasma; Ultrasound-guided injection. INTRODUCTION Peri-shoulder joint soft tissue inflammation is a group of the periarticular soft tissue disorders of shoulder, including ligaments, tendons, bursas. it often causes pain and reduces range of motion of the shoulder and affects patients’ quality of life. Perishoulder joint soft tissue inflammation .
